InterLymph hierarchical classification platform for i-CLASSi

About the i-CLASSi Tool

Disclaimer: This tool is developed for research and educational purposes only. It is not intended for clinical diagnosis or treatment guidance.

Overview

The InterLymph Consortium is an international scientific forum for epidemiologic research in lymphoid malignancies. i-CLASSi supports harmonized use of the InterLymph hierarchical classification of lymphoid neoplasms and related biomedical vocabularies.

InterLymph classification overview

Learn more at the InterLymph website.

Pathology Working Group

The InterLymph Pathology Working Group includes hematopathologists, epidemiologists, computational biologists, and researchers committed to harmonizing lymphoid malignancy classification for epidemiologic studies.

Citation

  1. Turner, J. J., et al. (2010). InterLymph hierarchical classification of lymphoid neoplasms for epidemiologic research based on the WHO classification (2008): update and future directions. Blood, 116(20), e90-e98.
  2. Morton, L. M., et al. (2007). Proposed classification of lymphoid neoplasms for epidemiologic research from the Pathology Working Group of InterLymph. Blood, 110(2), 695-708.
  3. Pathology Working Group (2025). InterLymph hierarchical classification of lymphoid neoplasms for epidemiologic research based on the WHO-HAEM5. Unpublished.

Data Sources

Detailed version-specific source snapshots, database counts, and reference builds are available in the Data Sources tab.

  • ICD-O-3 - International Classification of Diseases for Oncology, 3rd Edition
  • ICD-9 / ICD-10 / ICD-10-CM / ICD-11 - International Classification of Diseases vocabularies
  • SNOMED CT - Systematized Nomenclature of Medicine Clinical Terms
  • NCIt - NCI Thesaurus
  • EFO - Experimental Factor Ontology
  • UMLS CUI - Unified Medical Language System Concept Unique Identifiers

Team and Contributors

Webtool Development

  • Murat Güler (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany, murat.guler@dkfz.de)
  • Federico Canzian (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany)

Classification Contributors

  1. Alyssa Clay-Gilmour (Department of Epidemiology & Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA)
  2. Murat Güler (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany)
  3. James R. Cerhan (Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA)
  4. Karin E. Smedby (Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden)
  5. Arjan Diepstra (University Medical Center Groningen, Groningen, The Netherlands)
  6. InterLymph Consortium Pathology and Survival Working Group

Updates

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